Next-Generation Genomic Sequencing: Market Evaluation

A Panel Discussion Among Genomic Sequencing Experts

September 2007

Deliverable: Transcript with key findings

Study Description and Objectives

To assess potential future uptake of the Illumina 1G Genome Analyzer (using Solexa sequencing technology) and the competitive environment developing in the ‘next-generation sequencing’ space

§    From current Illumina/Solexa users, determine:

·     Drivers of initial adoption

·     Current utilization and applications

·     Levels of satisfaction with the product/technology

·     Strengths and weaknesses of the product

·     Appetite for additional purchases

§    From those (e.g., core labs and smaller academic centers) evaluating the Illumina/Solexa product and others, determine:

·     Existing platforms now in use

·     Barriers to adoption

·     Specific competing products under consideration

·     Purchasing criteria

·     Purchasing timelines

§    From all participants, explore the attributes, merits, and demerits of competing products, including:

·     Applied Biosystems SOLiD system (now in market via “early access program”)

·     454 Life Sciences sequencer (marketed by Roche Diagnostics)

·     Helicos Biosciences tSMS platform

§    Explore specific additional issues, including:

·     Thoughts on the potential for de novo sequencing using Illumina/Solexa, others

·     Time horizon for single-molecule sequencing, and who will get there first

·     Potential for longer read lengths being accommodated by any of the competitors

·     The future of capillary sequencing

·     Other competing technologies not previously discussed

Companies and Products Mentioned in This Report

Company

Ticker Symbol

Product(s)

Illumina/Solexa

ILMN

1G Genome Analyzer

Applied Biosystems

ABI

SOLiD

454 Life Sciences / Roche Diagnostics

 

Sequencer

Helicos Biosciences

HLCS

tSMS platform

 


Inclusion Criteria and Panelist Demographics

Inclusion Criteria

 

§    Experts in genomic sequencing

Represented Institutions

Hospital affiliation

State

Northwestern University

IL

Stanford University

CA

University of Washington

WA

Roswell Park Cancer Institute

NY

Duke University

NC

Cold Spring Harbor Laboratory

NY

Canada's Michael Smith Genome Sciences Centre

Vancouver, BC

Northwestern University

IL

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