Market Outlook for Drug Eluting Stents

    October 2009

Price:$2500

 

Deliverables: Survey Data Only

 

Please contact Howard.Brick@panelintelligence.com to purchase.

 

 

Project Objectives:

n  Primary Objective: To understand trends within the drug-eluting stent market

Study Scope and Participants:

n  Total Expert Consults: 50 Interventional Cardiologists

n  Screening Criteria:

·       US-based interventional cardiologists

·       Board-certified in specialty

·       2 to 30 years of experience post-residency

·       Minimum of 75% professional time spent in clinical practice

·       Implant at least 20 stents per month


   Market Outlook for Drug Eluting Stents (October 2009)

·                     Quota: 50 interventional cardiologists

·                     (Standard Intro Text)

Thank you for your participation in this survey. Your opinions are very important to us.

 

First, you will be asked a few questions to ensure you qualify for the survey. If you qualify, you will be presented with the survey which should take approximately 10 minutes to complete.

 

If you qualify and complete the survey you will receive the promised honorarium in appreciation of your time.

 

First Name:                                 

Last Name:                                 

E-mail Address:                          

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Screening Questions

S1.     What is your primary medical specialty?

  Cardiology

  Interventional cardiology

  Other, please specify                                 [Terminate]

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S2.     Approximately how many years have you been in practice since completing your residency?

           Years [Terminate if <2 or >30]

 

<Page Break>

 

S3.     Approximately what percentage of your professional time is dedicated to clinical practice?

           % Professional time in clinical practice [Terminate <75%]

<Page Break>     

S4.     On average, how many coronary stents do you place per month?

           Stents per month [Terminate <20]

 

<Page Break>     

Standard qualify text

<Page Break>     

<Page Break>              Market Outlook for Drug Eluting Stents (October 2009)

1.     During each of the time periods outlined below, please estimate how many bare metal stents and drug eluting stents (DES) you implanted.

 

Stent Type

Q1 ’09               (January – March)

Q2 ’09                           (April – June)

Q3 ’09                         (July - September)

Bare metal stents

 

 

 

Drug eluting stents

 

 

 

 

<Page Break>                 

2.       In the table below, please estimate how many bare metal stents and drug eluting stents (DES) you expect to implant between July and September of 2010.

Please note your previous responses have been included for reference.

 

Stent Type

Q3 ’09                                       (July – September 2009)

Q3 ’10                                       (July – September 2010)

Bare metal stents

<Pipe in Q1 response>

 

Drug eluting stents

<Pipe in Q1 response>

 

<Page Break>     

3.       Approximately how much do you currently pay for a DES?

  Less than $1,800

  $1,800 - $1,850

  $1,851 - $1,900

  More than $1,900

  I don’t know

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4.       How have DES prices changed in the past 3 months?

  Increased 4% or more

  Increased 1-3%

  Unchanged

  Decreased 1-3%

  Decreased 4-6%

  Decreased 7-10%

  Decreased 10% or more

  I don’t know (skip to Q6)

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5.       Over the past 3 months, have you seen any aggressive price cuts (defined as >5%) in specific drug-eluting stents?  Please select all that apply.

·                     [SELECT ALL THAT APPLY]

¨  I have seen >5% price cuts in Xience V stents

¨  I have seen >5% price cuts in Promus stents

¨  I have seen >5% price cuts in Taxus / Taxus Liberte stents

¨  I have seen >5% price cuts in Cypher stents

¨  I have seen >5% price cuts in Endeavor stents

¨  I have not seen price cuts of >5% for any DES (Exclusive)

<Page Break>     

6.       How do you expect DES prices to change in the next 6 months?

  Will increase by more than 10%

  Will increase 6-10%

  Will increase 1-5%

  Unchanged

  Will decrease 1-5%

  Will decrease 6-10%

  Will decrease by more than 10%

<Page Break>     

7.       For what percentage of your DES cases do you use each of the following products?

 

Please note your answers must sum to 100%.

·         rotate rows

Drug-Eluting Stent

Percentage of Total DES Cases

Xience V

 

Promus

 

Taxus / Taxus Liberte

 

Cypher

 

Endeavor

 

Other, please specify:_______

 

Total

[SUM TO 100%]

<Page Break>     


8.       In the third quarter of 2009 (July  – Sept 2009), which DES gained the most market share in your practice?

  Xience V

  Promus

  Taxus/Taxus Liberte

  Cypher

  Endeavor

  Other, please specify:_____

  None (skip to Q11)

<Page Break>     

9.       How many <insert Q8 selection> drug eluting stents did you implant in the third quarter of 2009 (Jul – Sep 2009) vs. the second quarter of 2009 (Apr – Jun 2009)?

 

Q2 2009: __________

Q3 2009: __________

·                     force q3 2009 greater than q2 2009 response

10.     What is the primary reason for this gain in market share?

  Superior clinical data

  Superior deliverability

  Favorable pricing/bundling

  Strength of sales rep

  Hospital contracting/administration is forcing a brand switch

  Involved in trials

  Other, please specify:______

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11.     Over the next six months, which DES do you expect will gain the most market share in your practice?

  Xience V

  Promus

  Taxus/Taxus Liberte

  Cypher

  Endeavor

  Other, please specify:_____

  None

<Page Break>     

 


The results of Spirit IV were presented at TCT on September 23 in San Francisco.   Spirit IV is a 3,690 patient head to head trial comparing Xience V versus Taxus Express.  The trial indicated that Xience V was superior to Taxus Express.   The primary endpoint was met for Xience V, with a 38% reduction in target lesion failure (TLF) compared to Taxus (4.2% for Xience compared to 6.8% for Taxus, p-value=0.001).   Safety for Xience V was also better, as Xience achieved a 74% reduction in stent thrombosis per ARC definition compared to Taxus (0.29% for Xience and 1.1% for Taxus, p=0.004).  

 

12.     Based on the Spirit IV results presented above, how would the percentage of DES cases in which you use each of the following products change?

 

          Your previous responses have been included for reference. Your answers must sum to 100%.

 

Drug-Eluting Stent

Current Percentage of           DES Cases

Percentage of DES Cases Based on Spirit IV

Xience V

<insert Q7 response>

 

Promus

<insert Q7 response>

 

Taxus / Taxus Liberte

<insert Q7 response>

 

Cypher

<insert Q7 response>

 

Endeavor

<insert Q7 response>

 

Other, please specify:_______

<insert Q7 response>

 

Total

 

MUST SUM TO 100%

<Page Break>     

In a diabetic subgroup that included ~1,200 patients in the Spirit IV trial, Xience demonstrated a favorable trend in target lesion failure (TLF) compared to Taxus (6.4% for Xience compared to 6.9% for Taxus, p-value=0.80).  

 

13.     Please estimate your usage of each DES product in your practice for the diabetic patient population only: 

      

Please note your answers must sum to 100%.

 

Drug-Eluting Stent

Percentage of DES Cases in Diabetics

Xience V

 

Promus

 

Taxus / Taxus Liberte

 

Cypher

 

Endeavor

 

Other, please specify:_______

 

Total

[SUM TO 100%]

 

<Page Break>     

·                     insert link to spirit Iv findings

14.     Previously you indicated using Xience V for <insert Q13_1>% of your DES implants among diabetic patients. Based on the Spirit IV results presented previously, how do you expect your utilization of Xience V to change in this population? 

 

__________ % of diabetic patients receiving Xience V based on Spirit IV results [Force > Q16_1]

<Page Break>     

15.     What percentage of procedures in your practice is small vessel?

 

%: _____ [If 0, End Survey]

<Page Break>     

16.     In what percentage of small vessel cases do you use TAXUS Atom?

 

%: __________

<Page Break>     

17.     Cypher was just approved in a 2.25mm version.  Based on this approval, what will be the new percentage of small vessel cases using the TAXUS Atom?

%: _____

·                     (END SURVEY)


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For additional information on this study or to purchase, please call:

Survey
Cardiology
Panel Intelligence, LLC, 150 Cambridgepark Drive, 7th Floor, Cambridge, MA 02140 617 532 5700